De novo binder design (24 hours)
De novo protein binder design (24 hours).
- Category
- Other
- Unit
- Score
- Higher is better
- Comparison groups
- 1total
- Currently available model rankings · Ranked results: 1
- All models (records): Groups: 1 · Entries: 3
Rankings
Values with different source types (official, third-party, paper) or measurement conditions cannot be compared, so rankings are separated by comparison group (the same source, or sources verified to use the same conditions).
Rankings include only models currently available in Claude Code / Codex, excluding legacy models.
official results (Introducing Claude Fable 5.2 and Claude Mythos 5.2)
| Rank | Model | effort | Score | Source cost (metric) | measured/reported by | source |
|---|---|---|---|---|---|---|
| 1 | Claude Opus 5.5 | not stated | 82.6 | — | Anthropic | Introducing Claude Fable 5.2 and Claude Mythos 5.2Retrieved 2026-11-12 · Vendor-reported value. table note: Scores for Fable 5.2, Fable 5.1, and Opus 5.5 show results with safeguards on unless otherwise noted. All scores show each model’s highest-available effort unless otherwise noted. Opus 5.5 without safeguards.Source excerpt82.6Location Table, Protein design row: 82.6 without safeguards |
All model rankings (records)
These rankings are recalculated by comparison group including legacy models and models unavailable in Claude Code / Codex. They differ from the rankings above because the set of models differs.
Show rankings including legacy and unavailable models (entries: 3)
official results (Introducing Claude Fable 5.2 and Claude Mythos 5.2)
| Rank | Model | effort | Score | Source cost (metric) | measured/reported by | source |
|---|---|---|---|---|---|---|
| 1 | Claude Mythos 5.2 | not stated | 85.1 | — | Anthropic | Introducing Claude Fable 5.2 and Claude Mythos 5.2Retrieved 2026-11-12 · Vendor-reported value. table note: Scores for Fable 5.2, Fable 5.1, and Opus 5.5 show results with safeguards on unless otherwise noted. All scores show each model’s highest-available effort unless otherwise noted.Source excerpt85.1Location Table, Protein design row: 85.1 Mythos 5.2 |
| 2 | Claude Opus 5.5 | not stated | 82.6 | — | Anthropic | Introducing Claude Fable 5.2 and Claude Mythos 5.2Retrieved 2026-11-12 · Vendor-reported value. table note: Scores for Fable 5.2, Fable 5.1, and Opus 5.5 show results with safeguards on unless otherwise noted. All scores show each model’s highest-available effort unless otherwise noted. Opus 5.5 without safeguards.Source excerpt82.6Location Table, Protein design row: 82.6 without safeguards |
| 3 | Claude Mythos 5.1 | not stated | 79.1 | — | Anthropic | Introducing Claude Fable 5.2 and Claude Mythos 5.2Retrieved 2026-11-12 · Vendor-reported value. table note: Scores for Fable 5.2, Fable 5.1, and Opus 5.5 show results with safeguards on unless otherwise noted. All scores show each model’s highest-available effort unless otherwise noted.Source excerpt79.1Location Table, Protein design row: 79.1 Mythos 5.1 |